| Protocol No. | ClinicalTrials.gov Protocol No. | PI Name | Title | |||
| Pediatric Cancers > Brain Tumors | ||||||
| ACCL2031 | NCT04939597 | Reddy, Alyssa | A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for a Brain Tumor | |||
| ACNS1422 | NCT02724579 | Reddy, Alyssa | Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma | |||
| ACNS1723 | NCT03919071 | Reddy, Alyssa | Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma | |||
| ACNS2021 | NCT04684368 | Reddy, Alyssa | A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT | |||
| PNOC005 | NCT02962167 | Mueller, Sabine | Modified Measles Virus (MV-NIS) for Children and Young Adults With Recurrent Medulloblastoma or Recurrent ATRT | |||
| PNOC008 | NCT03739372 | Mueller, Sabine | Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma | |||
| PNOC012 | NCT03579602 | Mueller, Sabine | Study of Tozuleristide and the Canvas Imaging System in Pediatric Subjects With CNS Tumors Undergoing Surgery | |||
| PNOC013 | NCT03690869 | Mueller, Sabine | REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma | |||
| PNOC017 | NCT03749187 | Mueller, Sabine | BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas | |||
| PNOC021 | NCT04485559 | Mueller, Sabine | Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas | |||
| PNOC022 | NCT05009992 | Mueller, Sabine | Combination Therapy for the Treatment of Diffuse Midline Gliomas | |||
| PNOC023 | NCT04732065 | Mueller, Sabine | ONC206 for Treatment of Newly Diagnosed, or Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors | |||
| PNOC025 | NCT05169944 | Mueller, Sabine | Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors | |||
| PNOC026 | NCT04775485 | Mueller, Sabine | A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors (FIREFLY-1) | |||
| Protocol No. | ClinicalTrials.gov Protocol No. | PI Name | Title | |||
| Pediatric Cancers > Brain Tumors or Solid Tumors | ||||||
| DFCI 18-284 | NCT03654716 | Vo, Kieuhoa | Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer | |||
| DFCI 16-371 | NCT02909777 | Vo, Kieuhoa | Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphoma | |||
| DFCI 20-041 | NCT04416568 | Reddy, Alyssa | Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers | |||
| PEPN2111 | NCT04870944 | Vo, Kieuhoa | CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma" | |||