Leukemia, Lymphoma, and Histiocytic Disorders

Protocol No. ClinicalTrials.gov Protocol No. PI Name Title
Pediatric Cancers > Leukemia and Lymphoma
AALL1721 NCT03876769 Hermiston, Michelle Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients (CASSIOPEIA)
AALL1821 NCT04546399 Huang, Benjamin A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
AALL1922 NCT04501614 Braun, Ben A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
ADVL1521 NCT03190915 Stieglitz, Elliot Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia
ADVL1822 NCT03793478 Vo, Kieuhoa Safety and Effectiveness of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood
ADVL2111 NCT05077423 Stieglitz, Elliot A Phase 1 Trial of CD33xCD3 BsAb in Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia
APAL2020SC NCT04726241 Stieglitz, Elliot The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
E4412 NCT01896999 Hermiston, Michelle Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
Protocol No. ClinicalTrials.gov Protocol No. PI Name Title
Pediatric Cancers > Histiocytic Disorders
NACHO LCH-IV NCT02205762 Hermiston, Michelle LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
NACHO HLHRUXO NCT04551131 Hermiston, Michelle Use Of A Response-Adapted Ruxolitinib-Containing Regimen For The Treatment Of Hemophagocytic Lymphohistiocytosis